鲁向锋，1977年生，籍贯山西，现任国家心血管病中心/中国医学科学院阜外医院流行病研究部主任、北京协和医学院博士生导师、科技部国家级重大人才项目入选者。主要从事心血管疾病等慢性病流行病学、遗传学和精准防治研究。在European Heart Journal、Nature Genetics、Am J Resp Crit Care Med、Science Bulletin等权威期刊发表100余篇SCI论文，获10项发明专利授权，成果写入国际经典教科书《Braunwald's Heart Disease》等10部中英专著，形成指南规范和指导防治实践工具，完成2000万元成果转化。

开展全国多中心队列人群随访研究和基因组等多组学研究，从宏观流病到分子水平揭示遗传和环境因素作用谱，创建国人基于环境和遗传因素的心血管疾病预测模型，形成个体化风险评估和分层技术及精准干预方案，指导精准防治。

1.Lu X#*, Liu Z, Cui Q, Liu F, Li J, Niu X, Shen C, Hu D, Huang K, Chen J, Xing X, Zhao Y, Lu F, Liu X, Cao J, Chen S, Ma H, Yu L, Wu X, Wu X, Li Y, Zhang H, Mo X, Zhao L, Huang J, Wang L, Wen W, Shu XO, Takeuchi F, Koh WP, Tai ES, Cheng CY, Wong TY, Chang X, Chan MY, Gao W, Zheng H, Chen K, Chen J, He J, Tang CS, Lam KSL, Tse HF, Cheung CYY, Takahashi A, Kubo M, Kato N, Terao C, Kamatani Y, Sham PC, Heng CK, Hu Z, Chen YE, Wu T, Shen H, Willer CJ and Gu D*. A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study. Eur Heart J. 2022; 43(18):1702-1711. (IF=35.855)

2. Zhao JV#*, Liu F, Schooling CM, Li J, Gu D and Lu X*. Using genetics to assess the association of commonly used antihypertensive drugs with diabetes, glycaemic traits and lipids: a trans-ancestry Mendelian randomisation study. Diabetologia. 2022; 65(4):695-704. (IF=10.46)

3. Lu X#*, Niu X#, Shen C, Liu F, Liu Z, Huang K, Wang L, Li J, Hu D, Zhao Y, Yang X, Lu F, Liu X, Cao J, Chen S, Li H, Tang W, Ren Z, Yu L, Wu X, Wu X, Li Y, Zhang H, Huang J, Hu Z, Shen H, Willer CJ and Gu D. Development and Validation of a Polygenic Risk Score for Stroke in the Chinese Population. Neurology. 2021; 97(6):e619-e628. (IF=11.80)

4. Li J#, Lu X*, Liu F, Liang F, Huang K, Yang X, Xiao Q, Chen J, Liu X, Cao J, Chen S, Shen C, Yu L, Lu F, Wu X, Zhao L, Wu X, Li Y, Hu D, Huang J, Zhu M, Liu Y, Shen H and Gu D. Chronic Effects of High Fine Particulate Matter Exposure on Lung Cancer in China. Am J Respir Crit Care Med. 2020; 202(11):1551-1559. (IF=30.528)

5.Huang K#, Yang X#, Liang F, Liu F, Li J, Xiao Q, Chen J, Liu X, Cao J, Shen C, Yu L, Lu F, Wu X, Zhao L, Wu X, Li Y, Hu D, Huang J, Liu Y, Lu X* and Gu D*. Long-Term Exposure to Fine Particulate Matter and Hypertension Incidence in China. Hypertension. 2019; 73(6):1195-1201. (IF=9.897)

6. Liu F#, Li J, Chen J, Hu D, Li Y, Huang J, Liu X, Yang X, Cao J, Shen C, Yu L, Liu Z, Wu X, Zhao L, Wu X, Gu D* and Lu X*. Predicting lifetime risk for developing atherosclerotic cardiovascular disease in Chinese population: the China-PAR project. Science Bulletin. 2018; 63(12):779-787. (IF=20.577)

7.Lu X#, Peloso GM, Liu DJ, Wu Y, Zhang H, Zhou W, Li J, Tang CS, Dorajoo R, Li H, Long J, Guo X, Xu M, Spracklen CN, Chen Y, Liu X, Zhang Y, Khor CC, Liu J, Sun L, Wang L, Gao YT, Hu Y, Yu K, Wang Y, Cheung CYY, Wang F, Huang J, Fan Q, Cai Q, Chen S, Shi J, Yang X, Zhao W, Sheu WH, Cherny SS, He M, Feranil AB, Adair LS, Gordon-Larsen P, Du S, Varma R, Chen YI, Shu XO, Lam KSL, Wong TY, Ganesh SK, Mo Z, Hveem K, Fritsche LG, Nielsen JB, Tse HF, Huo Y, Cheng CY, Chen YE, Zheng W, Tai ES, Gao W, Lin X, Huang W, Abecasis G, Consortium G, Kathiresan S, Mohlke KL, Wu T, Sham PC*, Gu D* and Willer CJ*. Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease. Nat Genet. 2017; 49(12):1722-1730. (IF=41.307)

8. Lu X#*, Huang J, Mo Z, He J, Wang L, Yang X, Tan A, Chen S, Chen J, Gu CC, Chen J, Li Y, Zhao L, Li H, Hao Y, Li J, Hixson JE, Li Y, Cheng M, Liu X, Cao J, Liu F, Huang C, Shen C, Shen J, Yu L, Xu L, Mu J, Wu X, Ji X, Guo D, Zhou Z, Yang Z, Wang R, Yang J, Yan W, Peng X and Gu D*. Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations. Circulation: Cardiovascular Genetics. 2016; 9(1):37-44. (IF=7.465)

9. Lu X#, Wang L#, Lin X#, Huang J#, Charles Gu C, He M, Shen H, He J, Zhu J, Li H, Hixson JE, Wu T, Dai J, Lu L, Shen C, Chen S, He L, Mo Z, Hao Y, Mo X, Yang X, Li J, Cao J, Chen J, Fan Z, Li Y, Zhao L, Li H, Lu F, Yao C, Yu L, Xu L, Mu J, Wu X, Deng Y, Hu D, Zhang W, Ji X, Guo D, Guo Z, Zhou Z, Yang Z, Wang R, Yang J, Zhou X, Yan W, Sun N, Gao P and Gu D*. Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension. Hum Mol Genet. 2015; 24(3):865-874. (IF=5.121, R, C100)

10. Lu X#, Wang L#, Chen S, He L, Yang X, Shi Y, Cheng J, Zhang L, Gu CC, Huang J, Wu T, Ma Y, Li J, Cao J, Chen J, Ge D, Fan Z, Li Y, Zhao L, Li H, Zhou X, Chen L, Liu D, Chen J, Duan X, Hao Y, Wang L, Lu F, Liu Z, Yao C, Shen C, Pu X, Yu L, Fang X, Xu L, Mu J, Wu X, Zheng R, Wu N, Zhao Q, Li Y, Liu X, Wang M, Yu D, Hu D, Ji X, Guo D, Sun D, Wang Q, Yang Y, Liu F, Mao Q, Liang X, Ji J, Chen P, Mo X, Li D, Chai G, Tang Y, Li X, Du Z, Liu X, Dou C, Yang Z, Meng Q, Wang D, Wang R, Yang J, Schunkert H, Samani NJ, Kathiresan S, Reilly MP, Erdmann J, Peng X, Wu X, Liu D, Yang Y, Chen R, Qiang B and Gu D*. Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. Nat Genet. 2012; 44(8):890-894. (IF=41.307, R, C100)