马艳妮,女,1981年出生,北京协和医学院准聘助理教授,研究员,博士生导师。2003年7月毕业于北京师范大学生物技术专业,学士;2008年7月毕业于中国医学科学院基础医学研究所生化与分子生物学系,理学博士。2008-2011年于中国科学院生物物理研究所任助理研究员。2011年7月加入中国医学科学院基础医学研究所生化与分子生物学系,医学分子生物学国家重点实验室工作。主要从事RNA与造血调控相关研究。
马艳妮
中国医学科学院基础医学研究所
助理教授
2021-07-01
生物学
生物化学与分子生物学
yanni_ma@126.com,mayanni@ibms.cams.cn
马艳妮,女,1981年出生,北京协和医学院准聘助理教授,研究员,博士生导师。2003年7月毕业于北京师范大学生物技术专业,学士;2008年7月毕业于中国医学科学院基础医学研究所生化与分子生物学系,理学博士。2008-2011年于中国科学院生物物理研究所任助理研究员。2011年7月加入中国医学科学院基础医学研究所生化与分子生物学系,医学分子生物学国家重点实验室工作。主要从事RNA与造血调控相关研究。
RNA代谢在多能干细胞、造血干细胞功能维持及分化中的调控机制研究。
1. Fengjiao Wang#, Jiahuan He#, Siqi Liu#, Ai Gao, Liu Yang, Guohuan Sun, Wanqiu Ding, Chuanyun Li, Fanglin Gou, Manman He, Fang Wang, Xiaoshuang Wang, Xiangnan Zhao, Ping Zhu, Shao Hao, Yanni Ma*, Hui Cheng*, Jia Yu*, Tao Cheng*. Comprehensive RNA editome reveals edited Azin1 as a novel DDX1 partner to facilitate hematopoietic stem cell differentiation. Blood. 2021 Nov 18;138(20):1939-1952. (IF=25.476) 2. Yanni Ma#*, Siqi Liu#, Jie Gao#, Chunyan Chen#, Xin Zhang#, Hao Yuan, Zhongyang Chen, Xiaolin Yin, Chenguang Sun, Yanan Mao, Fanqi Zhou, Yi Shao, Qian Liu, Jiayue Xu, Li Cheng, Daqi Yu, Pingping Li, Ping Yi, Jiahuan He, Guangfeng Geng, Qing Guo, Yanmin Si, Hualu Zhao, Haipeng Li, Graham L Banes, He Liu, Yukio Nakamura, Ryo Kurita, Yue Huang, Xiaoshuang Wang, Fang Wang, Gang Fang, James Douglas Engel, Lihong Shi*, Yong E Zhang*, Jia Yu*. Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia. Developmental Cell. 2021 Feb 22;56(4):478-493.e11. (IF=13.417) 3. Xue Wang#, Changyun Ping#, Puwen Tan#, Chenguang Sun, Guang Liu, Tao Liu, Shuchun Yang, Yanmin Si, Lijun Zhao, Yongfei Hu, Yuyan Jia, Xiaoshuang Wang, Meili Zhang, Fang Wang, Dong Wang*, Jia Yu*, Yanni Ma*, Yue Huang*. hnRNPLL controls pluripotency exit of embryonic stem cells by modulating alternative splicing of Tbx3 and Bptf. The EMBO Journal. 2021 Feb 15. 40(4):e104729. (IF=14.012) 4. Kai Li#, Jiayue Xu#, Yanyun Luo#, Dingfeng Zou, Ruiqin Han, Shunshun Zhong, Qing Zhao, Xinyu Mang , Mengzhen Li, Yanmin Si , Yan Lu, Pengyu Li, Cheng Jin, Zhipeng Wang, Fang Wang, Shiying Miao, Bo Wen, Linfang Wang, Yanni Ma*, Jia Yu*, Wei Song*. Panoramic transcriptome analysis and functional screening of long noncoding RNAs in mouse spermatogenesis. Genome Research. 2021 Jan. 31(1):13-26. (IF=9.438). 5. Zhengyi Zhang#, Jingnan Pi#, Dongling Zou#, Xiaoshuang Wang#, Jiayue Xu#, Shan Yu, Ting Zhang, Feng Li, Hualu Zhao, Fang Wang, Dong Wang*, Yanni Ma*, Jia Yu*. microRNA arm-imbalance partially from targets-mediated decay promotes gastric cancer progression. Nature Communications. 2019 Sep 27. 10(1):4397. (IF=17.694) 6. Jie Zhou#, Jiayue Xu#, Lingling Zhang#, Siqi Liu#, Yanni Ma#, Xin Wen, Junkai Hao, Zongcheng Li, Yanli Ni, Xianlong Li, Fan Zhou, Qingqing Li, Fang Wang, Xiaoshuang Wang, Yanmin Si, Pengcheng Zhang, Chen Liu, Marisa Bartolomei, Fuchou Tang, Bing Liu*, Jia Yu*, Yu Lan*. Combined Single-Cell Profiling of lncRNAs and Functional Screening Reveals that H19 Is Pivotal for Embryonic Hematopoietic Stem Cell Development. Cell Stem Cell. 2019 Feb 7. 24(2):285-298.e5. (IF=25.269, F1000) 7. Yanni Ma#, Nan Yao#, Guang Liu#, Lei Dong, Fang Wang, Bin Wang, He Dong, Xueju Wei, Meili Zhang, Shaowei Ji, Yufang Liu, Junwu Zhang, Yangming Wang, Yue Huang*, Jia Yu*. Functional screen reveals essential roles of miR-27a/24 in differentiation of embryonic stem cell. The EMBO Journal. 2015 Feb 3. 34(3):361–378. (IF=14.012) 8. Yanni Ma#, Bin Wang#, Fengbing Jiang#, Dongsheng Wang#, Huiwen Liu, Yunmeng Yan, He Dong, Fang Wang, Bei Gong, Yong Zhu, Lei Dong, Haixin Yin, Zhongzu Zhang, Hualu Zhao, Zhikui Wu, Junwu Zhang, Jingguo Zhou, Jia Yu, Jia Yu*. A Feedback Loop Consisting of MicroRNA 23a/27a and the Beta-Like Globin Suppressors KLF3 and SP1 Regulates Globin Gene Expression. Molecular and Cellular Biology. 2013 Oct; 33(20):3994-4007. (IF=5.069)