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肿瘤医院

  • 姓 名:

    程书钧

  • 单 位:

    中国医学科学院肿瘤医院

  • 教职岗位:

    教授

  • 聘任时间:

    2018-07-01

  • 一级学科:

    临床医学

  • 二级学科:

    肿瘤学

  • 联系方式:

    chengshj@cae.cn

  • 导师风采链接:

个人简介

程书钧,1939年生,籍贯浙江临安,肿瘤病因学家,肿瘤医院研究员,博士生导师。1957年考入北京医学院医疗系,1962年考入中国协和医科大学病理系实验肿瘤专业研究生,1965年研究生毕业。1985年升为副研究员。1989年为研究员。1999年当选为中国工程院院士。


主要研究方向

衰老(宿主因素)和恶性肿瘤的发生、发展,及带瘤生存的研究。


代表性成果

1. Zhang Q#, Kuang M, An H, Zhang Y, Zhang K, Feng L, Zhang L*, Cheng S*. Peripheral blood transcriptome heterogeneity and prognostic potential in lung cancer revealed by RNA-Seq. J Cell Mol Med. 2021 Sep;25(17):8271-8284. (IF=4.829)

2. Wang X#, Wang Y#, Feng L, Wang M, Zhang K, Mao Y*, Xiao T*, Cheng S*. Elevated expression of lung development-related protein HSP90β indicates poor prognosis in non-small cell lung cancer through affecting the cell cycle and apoptosis. Signal Transduct Target Ther. 2021 Feb 26;6(1):82. (IF=38.10)

3. Ding N#, Zhang B#, Ying W#, Song J, Feng L, Zhang K, Li H, Xu J*, Xiao T*, Cheng S*. A time-resolved proteotranscriptomics atlas of the human placenta reveals pan-cancer immunomodulators. Signal Transduct Target Ther. 2020 Jun 30;5(1):110. (IF=38.104)

4. Zhang B#, Wang Y, Li H, Feng L*, Li W*, Cheng S*. Identification of Prognostic Biomarkers for Multiple Solid Tumors Using a Human Villi Development Model. Front Cell Dev Biol. 2020 Jun 23;8:492. (IF=6.081)

5. Shen R#, Li P#, Li B, Zhang B, Feng L*, Cheng S*. Identification of Distinct Immune Subtypes in Colorectal Cancer Based on the Stromal Compartment. Front Oncol. 2020 Jan 10;9:1497. (IF=5.738)

6. Xu J#, Feng L#, Han Z#, Li Y#, Wu A, Shao T, Ding N, Li L, Deng W, Di X, Wang J, Zhang L*, Li X*, Zhang K*, Cheng S*. Extensive ceRNA-ceRNA interaction networks mediated by miRNAs regulate development in multiple rhesus tissues. Nucleic Acids Res. 2016 Nov 2;44(19):9438-9451. (IF=19.16)

7. Li M#, Xiao T#, Zhang Y, Feng L, Lin D, Liu Y, Mao Y, Guo S, Han N, Di X, Zhang K, Cheng S*, Gao Y*. Prognostic significance of matrix metalloproteinase-1 levels in peripheral plasma and tumour tissues of lung cancer patients. Lung Cancer. 2010 Sep;69(3):341-7. (IF=6.081)

8. Xiao T#, Ying W, Li L, Hu Z, Ma Y, Jiao L, Ma J, Cai Y, Lin D, Guo S, Han N, Di X, Li M, Zhang D, Su K, Yuan J, Zheng H, Gao M, He J, Shi S, Li W, Xu N, Zhang H, Liu Y, Zhang K*, Gao Y*, Qian X*, Cheng S*. An approach to studying lung cancer-related proteins in human blood. Mol Cell Proteomics. 2005 Oct;4(10):1480-6. (IF=7.381)

9.Zhang J#, Fan Z, Gao Y, Xiao Z, Li C, An Q, Cheng S*. Detecting bladder cancer in the Chinese by microsatellite analysis: ethnic and etiologic considerations. J Natl Cancer Inst. 2001 Jan 3;93(1):45-50. (IF=11.816)