张学，1964年生，籍贯黑龙江省大庆市，医学遗传学家，博士生导师，现任中国医学科学院基础医学研究所医学遗传学系主任、长聘教授，哈尔滨医科大学校长。1994年于中国医科大学细胞生物学专业获得博士学位。1989年-2002年，担任中国医科大学基础医学院医学遗传学教研室助教、讲师。2001年至今，担任中国医学科学院基础医学研究所医学遗传学系主任。2018年，担任哈尔滨医科大学校长。2019年，当选为中国工程院院士。

利用人类基因组研究的成果和我国的家系资源优势，进行单基因遗传病和多种出生缺陷致病基因的识别和功能研究以及基因组病遗传缺陷的鉴定。

1.Chao Ling#, Yi Dai, Li Fang, Fengxia Yao, Zhe Liu, Zhengqing QiuLiying Cui, Fan Xia, Chen Zhao, Shuyang Zhang, Kai Wang*, Xue Zhang*. Exonic rearrangements in DMD in Chinese Han individuals affected with Duchenne and Becker muscular dystrophies. Hum Mutat. 2020 Mar;41(3):668-677. (IF=4.700)

2. Xiao-Jian Wang#, Xi-Qi Xu#, Kai Sun#, Ke-Qiang Liu, Su-Qi Li, Xin      

Jiang, Qin-Hua Zhao, Lan Wang, Fu-Hua Peng, Jue Ye, Yan Wu, Rui Jiang, Jin Zhang, Wei Huang, Wen-Bin Wei, Yi Yan, Jing-Hui Li, Qian-Qian Liu, Sheng Li, Yong Wang, Shu-Yang Zhang, Xue Zhang*, Zhi-Cheng Jing*. Association of Rare PTGIS Variants With Susceptibility and Pulmonary Vascular Response in Patients With Idiopathic Pulmonary Arterial Hypertension. JAMA Cardiol. 2020 Jun 1;5(6):677-684. (IF=30.154)

3. Jun Yang#, Lianqing Wang, Yingzhi Huang, Keqiang Liu, Chaoxia Lu, Nuo Si, Rongrong Wang, Yaping Liu*, Xue Zhang*. Keratin 5-Cre-driven deletion of Ncstn in an acne inversa-like mouse model leads to a markedly increased IL-36a and Sprr2 expression. Front Med. 2020 Jun;14(3):305-317. (IF=9.927)

4. Liang Cheng#, Changlu Qi, He Zhuang, Tongze Fu, Xue Zhang*. gutMDisorder: a comprehensive database for dysbiosis of the gut microbiota in disorders and interventions. Nucleic Acids Res. 2020 Jan 8;48(D1):D554-D560. (IF=19.160)

5. Lulu Li#, Bin Mao#, Shan Li#, Jifang Xiao, Han Wang, Jing Zhang, Xiuzhi Ren, Yanzhou Wang, Yiyang Wu, Yixuan Cao, Chaoxia Lu, Jinsong Gao, Yi You, Feiyue Zhao, Xingzhu Geng, Yaxiong Xiao, Chendan Jiang, Yuqian Ye, Tao Yang, Xiuli Zhao*, Xue Zhang*. Genotypic and phenotypic characterization of Chinese patients with osteogenesis imperfecta. Hum Mutat. 2019 May;40(5):588-600. (IF=4.700)

6. Chaoxia Lu#, Wei Wu#, Fang Liu, Kunqi Yang, Jiacheng Li, Yaping Liu, Rongrong Wang, Nuo Si, Peng Gao, Yongtai Liu, Shuyang Zhang*, Xue Zhang*. Molecular analysis of inherited cardiomyopathy using next generation semiconductor sequencing technologies. J Transl Med. 2018 Aug 30;16(1):241. (IF=8.440)

7. Xiaonan Liu#, Chao Zhang#, Kewu Liu, Han Wang, Chaoxia Lu, Hang Li, Kai Hua, Juanli Zhu, Wenli Hui, Yali Cui*, Xue Zhang*. Multiple SNPs Detection Based on Lateral Flow Assay for Phenylketonuria Diagnostic. Anal Chem. 2018 Mar 6;90(5):3430-3436. (IF=8.008)

8. Fang Liu#, Qing Liu#, Chao Xia Lu, Bo Cui, Xia Nan Guo, Rong Rong Wang, Ming Sheng Liu, Xiao Guang Li, Li-Ying Cui, Xue Zhang*. Identification of a novel loss-of-function C9orf72 splice site mutation in a patient with amyotrophic lateral sclerosis. Neurobiol Aging. 2016 Nov;47:219.e1-219.e5. (IF=5.133)

9. Qing Liu#, Fang Liu#, Bo Cui, Chao Xia Lu, Xia Nan Guo, Rong Rong Wang, Ming Sheng Liu, Xiao Guang Li, Li-Ying Cui*, Xue Zhang*. Mutation spectrum of Chinese patients with familial and sporadic amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry. 2016 Nov;87(11):1272-1274. (IF=13.654)

10. Qing Liu#, Shi Shu#, Rong Rong Wang, Fang Liu, Bo Cui, Xia Nan Guo, Chao Xia Lu, Xiao Guang Li, Ming Sheng Liu, Bin Peng, Li-Ying Cui, Xue Zhang*. Whole-exome sequencing identifies a missense mutation in hnRNPA1 in a family with flail arm ALS. Neurology. 2016 Oct 25;87(17):1763-1769. (IF=11.800)