黄波，2002年在华中科技大学同济医学院生物化学与分子生物学系，获得博士学位。于2002年-2006年，先后在瑞典Karolinska Institute（乳腺癌的遗传学）、加拿大University of Calgary（脑胶质瘤的生物学）、美国Mount Sinai School of Medicine（肿瘤免疫学和免疫治疗）从事博士后研究。2006年初回国，任华中科技大学同济医学院生物化学与分子生物学系副教授，2008年破格晋升为教授、博士生导师，2012年调入医科院基础所免疫系从事肿瘤免疫方向的研究，现任中国医学科学院基础医学研究所副所长。

围绕肿瘤免疫治疗，T细胞和肿瘤代谢，肿瘤生物治疗，肿瘤生物机械力，干细胞体外培养及扩增，肿瘤休眠，CAR-T细胞治疗以及临床免疫治疗等方面开展了深入研究。

1. Zhang H#, Liu J, Yang Z, Zeng L, Wei K, Zhu L, Tang L, Wang D, Zhou Y, Lv J, Zhou N, Tang K, Ma J, Huang B*. TCR activation directly stimulates PYGB-dependent glycogenolysis to fuel the early recall response in CD8+ memory T cells. Molecular Cell. 2022;17:S1097-2765(22)00538-X. (IF=17.970)

2. Lv J#, Liu Y, Mo S, Zhou Y, Chen F, Cheng F, Li C, Saimi D, Liu M, Zhang H, Tang K, Ma J, Wang Z, Zhu Q, Tong WM, Huang B*. Gasdermin E mediates resistance of pancreatic adenocarcinoma to enzymatic digestion through a YBX1-mucin pathway. Nature Cell Biology. 2022;24:364-72. (IF=28.123)

3. Liu Y#, Zhou N#, Zhou L#, Wang J, Zhou Y, Zhang T, Fang Y, Deng J, Gao Y, Liang X, Lv J, Wang Z, Xie J, Xue Y, Zhang H, Ma J, Tang K, Fang Y, Cheng F, Zhang C, Dong B, Zhao Y, Yuan P, Gao Q, Zhang H, Xiao-Feng Qin F, Huang B*. IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor. Nature Immunology. 2021;22(3):358-369. (IF=31.25)

4. Lv J#, Liu Y, Cheng F, Li J, Zhou Y, Zhang T, Zhou N,Wang N, Liu Y, Huang B*. Cell softness regulates tumorigenicity and stemness of cancer cells. EMBO J.2021;40(2):e106123. (IF=14.012)

5. Gao Y#, Zhang H, Zhou N, Xu P, Wang J, Gao Y, Jin X, Liang X, Lv J, Zhang Y, Tang K, Ma J, Zhang H, Xie J, Yao F, Tong W, Liu Y, Wang X, Huang B*. Methotrexate-loaded tumour-cell-derived microvesicles can relieve biliary obstruction in patients with extrahepatic cholangiocarcinoma. Nature Biomedical Engineering.2020;4(7):743-53. (IF=25.671)

6. Zhang H#, Tang K, Ma J, Zhou L, Liu J, Zeng L, Zhu L, Xu P, Chen J, Wei K, Liang X, Lv J, Xie J, Liu Y, Wan Y, Huang B*. Ketogenesis-generated β-hydroxybutyrate is an epigenetic regulator of CD8+ T cell memory development. Nature Cell Biology.2020;22(1):18-25. (IF=28.824)

7. Liu Y#,  Fang Y#,  Chen X,  Wang Z,  Liang X,  Zhang T,  Liu M,  Zhou N,  Lv J,  Tang K,  Xie J,  Gao Y,  Cheng F,  Zhou Y,  Zhang Z,  Hu Y,  Zhang X,  Gao Q,  Zhang Y,  Huang B*. Gasdermin E–mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome. Science Immunology.2020;5(43):eaax7969. (IF=17.727, C100)

8.Liu Y#, Liang X#, Dong W, Lv J, Fiskesund R, Xie J, Jin X, Degao Chen, Mo S, Zhang T, Cheng F, Zhou Y, Zhang H, Wang J, Hu Z, Cao X, Qin F, Huang B*. Tumor-repopulating cells transfer kynurenine to upregulate PD-1 expression in tumor-specific CD8+ T cells through AhR activation. Cancer Cell.2018;33:480-494. (IF=23.916)

9. Ma R#, Ji T#, Zhang H, Dong W, Chen X, Xu P, Chen D, Ma J, Tang K, Zhang Y, Peng Y, Lu J, Zhang Y, Qin X, Cao X, Wan Y, Huang B*. A Pck1-directed glycogen 1 metabolic program regulates formation and maintenance of memory CD8+ T cells. Nature Cell Biology.2018;20:21-27. (IF=23.916)

10. Liu J#, Tan Y, Zhang H, Zhang Y, Xu P, Chen J, Poh YC, Tang K, Wang N, Huang B*. Soft fibrin gels promote selection and growth of tumorigenic cells. Nature Materials.2012;11(8):734-41. (IF= 32.841, C100)