蒋澄宇，1964年生，生物化学与分子生物学家，中国医学科学院基础医学研究所研究员，博士生导师。1988年毕业于中国科学技术大学生物系，获理学学士学位；1996年毕业于美国布朗大学医学院病理与实验室药学系，获博士学位。随后于哈佛医学院麻省总医院从事博士后工作。 2003年至今，中国医学科学院基础医学研究所教授。

致力于植物药新主流有效成分小RNA的药效和递送系统研发，以及病毒等引起的呼吸衰竭的机制和治疗研究，发现ARB类药物对SARS、禽流感、微纳米颗粒及SARS-CoV-2感染引发的重症肺炎及多器官衰竭有很好的治疗效果并显著降低了治疗组死亡率。

1. Zhao Y#, Huang F#, Zou Z#, Bi Y#, Yang Y#, Zhang C, Liu Q, Shang D, Yan Y, Ju X, Mei S, Xie P, Li X, Tian M, Tan S, Lu H, Han Z, Liu K, Zhang Y, Liang J, Liang Z, Zhang Q, Chang J, Liu WJ, Feng C, Li T, Zhang MQ, Wang X, Gao GF, Liu Y*, Jin N*, Jiang C*. Avian influenza viruses suppress innate immunity by inducing trans-transcriptional readthrough via SSU72. Cell Mol Immunol, 2022. 19(6):702-714. (IF=22.096)

2. Liu Y#, Zhang C#, Huang F#, Yang Y#, Wang F, Yuan J, Zhang Z, Qin Y, Li X, Zhao D, Li S, Tan S, Wang Z, Li J, Shen C, Li J, Peng L, Wu W, Cao M, Xing L, Xu Z, Chen L, Zhou C, Liu WJ*, Liu L*, Jiang C*. Elevated plasma levels of selective cytokines in COVID-19 patients reflect viral load and lung injury. Natl Sci Rev, 2020.7(6):1003-1011. (IF=23.178, C100, ESI)

3. Liu Y#*, Yang Y#, Zhang C#, Huang F#, Wang F, Yuan J, Wang Z, Li J, Li J, Feng C, Zhang Z, Wang L, Peng L, Chen L, Qin Y, Zhao D, Tan S, Yin L, Xu J, Zhou C, Jiang C*, Liu L*. Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury. Sci China Life Sci, 2020. 63(3):364-374. (IF=10.372, C100, ESI)

4. Yan F#, Huang F#, Xu J#, Yang P#, Qin Y#, Lv J#, Zhang S, Ye L, Gong M, Liu Z, Wei J, Xie T, Xu KF, Gao GF, Wang FS, Cai L*, Jiang C*. Antihypertensive drugs are associated with reduced fatal outcomes and improved clinical characteristics in elderly COVID-19 patients. Cell Discov, 2020. 6(1):77. (IF=38.079)

5. Yang Y#, Shen C#, Li J#, Yuan J, Wei J, Huang F, Wang F, Li G, Li Y, Xing L, Peng L, Yang M, Cao M, Zheng H, Wu W, Zou R, Li D, Xu Z, Wang H, Zhang M, Zhang Z, Gao GF, Jiang C*, Liu L*, Liu Y*. Plasma IP-10 and MCP-3 levels are highly associated with disease severity and predict the progression of COVID-19. J Allergy Clin Immunol, 2020. 146(1):119-127.e4. (IF=14.290, C100, ESI)

6. Li X#, Liang Z#, Du J#, Wang Z#, Mei S, Li Z, Zhao Y, Zhao D, Ma Y, Ye J, Xu J, Zhao Y, Chang J, Qin Y, Yu L, Wang C*, Jiang C*. Herbal decoctosome is a novel form of medicine. Sci China Life Sci, 2019. 62(3):333-348. (IF=10.372)

7. Huang F#, Du J#, Liang Z#, Xu Z, Xu J, Zhao Y, Lin Y, Mei S, He Q, Zhu J, Liu Q, Zhang Y, Qin Y, Sun W, Song J, Chen S, Jiang C*. Large-scale analysis of small RNAs derived from traditional Chinese herbs in human tissues. Sci China Life Sci, 2019. 62(3):321-332. (IF=10.372)

8. Zou Z#, Yan Y#, Shu Y#, Gao R#, Sun Y, Li X, Ju X, Liang Z, Liu Q, Zhao Y, Guo F, Bai T, Han Z, Zhu J, Zhou H, Huang F, Li C, Lu H, Li N, Li D, Jin N*, Penninger JM*, Jiang C*. Angiotensin-converting enzyme 2 protects from lethal avian influenza A H5N1 infections. Nat Commun, 2014. 6(5):3594. (IF=17.694, C100, ESI)

9. Wang H#, Yang P, Liu K, Guo F, Zhang Y, Zhang G, Jiang C*. SARS coronavirus entry into host cells through a novel clathrin- and caveolae-independent endocytic pathway. Cell Res, 2008.18(2):290-301. (IF=46.297, C100)

10. Kuba K#, Imai Y#, Rao S#, Gao H, Guo F, Guan B, Huan Y, Yang P, Zhang Y, Deng W, Bao L, Zhang B, Liu G, Wang Z, Chappell M, Liu Y, Zheng D, Leibbrandt A, Wada T, Slutsky AS, Liu D, Qin C, Jiang C*, Penninger JM. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat Med, 2005. 11(8):875-9. (IF=87.241, C100)